Blood Doping sports |
Blood Doping Sports
The test was introduced in 2004 which is able to detect the use of homologous transfusion and the use of artificial oxygen carriers. Although the appropriate test has not been developed to detect an autologous blood doping.
After the development of the EPO, a blood doping usage go down much, but due to the development of tests for the detection of EPO and the lack of testing for an autologous doping, it is again on the rise.
EPO and side effects
EPO is a hormone peptides that are produced naturally by the human body. EPO is released from the kidneys and work on the bone marrow to stimulate the production of red blood cells. An increase in red blood cells increases the amount of oxygen that the blood can carry to the body's muscles. It can also increase the capacity of the body to buffer lactic acid.
While proper use of EPO has an enormous therapeutic benefit in the treatment of anemia related to kidney disease, misuse can lead to serious health risks for athletes who use this substance simply to gain a competitive advantage. It is well known that EPO, by thickening the blood, causing an increased risk of deadly diseases some, such as heart disease, stroke, and pulmonary emboli or brain. Recombinant human EPO abuse can also cause autoimmune diseases with serious health consequences.
A TEST TO DETECT EPO
A test for EPO was introduced at the 2000 Summer Olympics in Sydney (Australia). Tests, validated by the International Olympic Committee (IOC), is based on blood and urine matrix. A blood screening is performed first and then the urine test is used to confirm the possibility of use of EPO.
In June 2003, WADA's Executive Committee who received the results of an independent report stating that urine tests alone can be used to detect the presence of recombinant EPO. This report, requested by WADA stakeholders and is assigned by the Agency to evaluate the validity of urine and blood tests to detect the presence of recombinant EPO, concluded that urine tests are the only validated scientific methods for direct detection of recombinant EPO. The report also recommends that urine tests can be used in conjunction with blood screening for a variety of reasons, including the cost savings of doing screening blood before urine testing. Some International Federations still use both urine and blood matrix for detecting EPO. Recently, the urine tests used to detect some agent stimulates new eritropoiesis adapted for a blood test.
SYNTHETIC OXYGEN
Synthetic oxygen carriers, such as hemoglobin-based oxygen carriers (HBOCs) or perflurocarbons (PFC), purified proteins or chemicals having the ability to carry oxygen.
Synthetic oxygen carriers appear useful for the purposes of emergency medicines when human blood is not available, the risk of blood infection is high or when there is not enough time to properly cross-match donated blood with the recipient. However, their misuse for doping purposes carries the risk of cardiovascular disease in addition to various serious side effects (e.g., stroke, myocardial infarction, emboli).
However, synthetic oxygen can already detected a test which was carried out in 2004.
BLOOD TRANSFUSIONS FOR DOPING
There are two forms of blood doping: an autologous and homologous. Blood doping is an autologous blood transfusion itself, which has been stored (refrigerated or frozen) until needed. Homologous blood doping is the transfusion of blood that had been taken from another person with the same blood type. Although the use of blood transfusions for blood doping dates back several decades, the recent revival may be due to the introduction of efficient EPO detection methods.
Then do a test for homologous blood transfusion (HBT) held at the 2004 Summer Olympics in Athens. WADA funded research project aimed at developing a test for an autologous transfusion.
In order to further enhance the detection of the abnormal blood profiles, WADA is leading the development of strategies against doping in the sport called athlete's Passport, based on the athlete's biological variables follow from time to time. The goal of this strategy, which will be added to the anti-doping strategies including traditional testing is to detect abnormal variations of biological variables are determined to better target testing and/or sanction those found with abnormal variations.
SIDE EFFECTS OF DOPING BY BLOOD TRANSFUSION
Like other forms of blood doping, transfusions have serious medical consequences. The blood of others may contain viruses, which accidentally transmitted during transfusions. An athlete using his own blood, was able to put myself on a significant health risk if such a procedure is not done properly or if the blood is not handled or stored in a proper way. In addition, the red blood cell levels are reasonably high increases the risk of heart attack, stroke, and pulmonary emboli or brain.
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